Left alone with two young daughters after the accidental death of her beloved husband Pierre Curie, Marie Curie faces her duties with greatest courage as a mother and a scientist. But science is primarily a man’s world and Marie’s audacity is not well seen by everybody. As she embarks on a passionate affair with the mathematician Paul Langevin, she provokes a huge scandal and the tabloids drag her name through the mud. Alarmed by all the malevolent headlines, the Swedish Nobel Academy, who wants to award her a second Nobel Prize (making her the first person ever to receive two), forbids her to drive to Stockholm to fetch her award.